Blood cells

most common type of blood cell

type of cells of the immunological system

cell produced by hematopoiesis

stem cell type that gives rise to other blood cells

In hematology, reticulocytes are immature red blood cells (RBCs). In the process of erythropoiesis (red blood cell formation), reticulocytes develop and mature in the bone marrow and then circulate for about a day in the blood stream before developing into mature red blood cells. Like mature red blood cells, in mammals, reticulocytes do not have a cell nucleus. They are called reticulocytes because of a reticular (mesh-like) network of ribosomal RNA that becomes visible under a microscope with certain stains such as new methylene blue and Romanowsky stain.

cell type; precursor of erythrocytes

red blood cells separated for blood transfusion

thumb|Lymphoblast __NOTOC__ A lymphoblast is a modified naive lymphocyte with altered cell morphology. It occurs when the lymphocyte is activated by an antigen and increased in volume by nucleus and cytoplasm growth as well as new mRNA and protein synthesis. The lymphoblast then starts dividing two to four times every 24 hours for three to five days, with a single lymphoblast making approximately 1000 clones of its original naive lymphocyte, with each clone sharing the originally unique antigen specificity. Finally the dividing cells differentiate into effector cells, known as plasma cells (fo

tissue of bone marrow

The myeloblast is a unipotent white blood cell which differentiates into the effectors of the granulocyte series. It is found in the bone marrow. Stimulation of myeloblasts by G-CSF and other cytokines triggers maturation, differentiation, proliferation and cell survival.

A promyelocyte (or progranulocyte) is a granulocyte precursor, developing from the myeloblast and developing into the myelocyte. Promyelocytes measure 12–20 microns in diameter. The nucleus of a promyelocyte is approximately the same size as a myeloblast but their cytoplasm is much more abundant. They also have less prominent nucleoli than myeloblasts and their chromatin is more coarse and clumped. The cytoplasm is basophilic and contains primary red/purple granules.

chemical compound

A proerythroblast (or rubriblast, or pronormoblast) is a precursor cell to the normoblast (nucleated red blood cell), as the earliest of four stages in its development.

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thumb|right|blood film in a patient with [[hereditary elliptocytosis: approximately 60% to 70% of the RBCs are elliptocytes.]] thumb|Elliptocyte compared to other forms of poikilocytosis.

CFU-GEMM is a colony forming unit that generates myeloid cells. CFU-GEMM cells are the oligopotential progenitor cells for myeloid cells; they are thus also called common myeloid progenitor cells or myeloid stem cells. "GEMM" stands for granulocyte, erythrocyte, monocyte, megakaryocyte.

thumb|Promegakaryocyte

cells found in the blood and organs of guinea pigs and capybara

thumb|400px|Comparison of monoblast, promonocyte and monocyte.

CFU-GM (Colony Forming Unit–Granulocyte–Macrophage), also known as granulocyte–macrophage progenitor (GMP), is a colony forming unit. It is derived from CFU-GEMM. It is the precursor for monoblasts and myeloblasts. Production is stimulated by granulocyte macrophage colony-stimulating factor (GM-CSF).

A microcyte is an abnormally sized red blood cell. By definition, it is 5 micrometers or smaller in diameter with a mean corpuscular value less than 80fL. It is often associated with several forms of anemia. Microcytes are associated with the most common cause of anemia in children and adults. Many causes of microcytes can be seen at birth; however, some variations are acquired. The most common cause of microcytes is iron availability and/or iron metabolism.