Coagulopathies

In hematology, thrombocytopenia is a condition characterized by abnormally low levels of platelets (also known as thrombocytes) in the blood. Low levels of platelets in turn may lead to prolonged or excessive bleeding. It is the most common coagulation disorder among intensive care patients and is seen in a fifth of medical patients and a third of surgical patients.

pathological process characterized by the widespread activation of the clotting cascade that results in the formation of blood clots in the small blood vessels throughout the body

primary thrombocytopenia that involves relatively few platelets in blood as a result of autoantibodies

formation of a blood clot (thrombus) in a deep vein

blood-clotting disorder

human disease

thumb|Histopathological image representing a [[bone marrow aspirate in a patient with essential thrombocythemia]]

Coagulopathy (also called a bleeding disorder) is a condition in which the blood's ability to coagulate (form clots) is impaired. This condition can cause a tendency toward prolonged or excessive bleeding (bleeding diathesis), which may occur spontaneously or following an injury or medical and dental procedures.

human disease

Thrombophilia (sometimes called hypercoagulability or a prothrombotic state) is an abnormality of blood coagulation that increases the risk of thrombosis (blood clots in blood vessels). Such abnormalities can be identified in 50% of people who have an episode of thrombosis (such as deep vein thrombosis in the leg) that was not provoked by other causes. A significant proportion of the population has a detectable thrombophilic abnormality, but most of these develop thrombosis only in the presence of an additional risk factor.

X-linked disease that has material basis in Factor VIII deficiency, which results in the formation of fibrin deficient clots which makes coagulation much more prolonged

inherited blood coagulation disease that has material basis in Factor IX deficiency, which makes coagulation much more prolonged. The disease is inherited as an X-linked recessive trait

human disease

human disease

development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin, an anticoagulant

human disease

variant causing increased blood clotting

Human disease

Human disease

Human disease

rare disease

pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury

Blood clot in a vein near the skin surface

rare disease usually seen in infants

human disease

medical condition

medical condition

inherited blood coagulation disease characterized by the tendency to form clots in the veins

disorder associated with increased risk of venous thrombosis

platelet-related disease affecting fetuses and infants, which can be fatal

hemostatic disorder

rare genetic trait that predisposes to thrombotic disease

purpura characterized by blood spots, bruising and discolouration of the skin

Hypoprothrombinemia is a rare blood disorder in which a deficiency in immunoreactive prothrombin (Factor II), produced in the liver, results in an impaired blood clotting reaction, leading to an increased physiological risk for spontaneous bleeding. This condition can be observed in the gastrointestinal system, cranial vault, and superficial integumentary system, affecting both the male and female population. Prothrombin is a critical protein that is involved in the process of hemostasis, as well as illustrating procoagulant activities. This condition is characterized as an autosomal recessive

rare congenital autosomal recessive bleeding disorder caused by a reduction or absence of alpha-granules in blood platelets