thrombophilia
Sign in to saveAlso known as Thrombophilia (disorder), hypercoagulability state (finding), prothrombotic state, hypercoagulability state, Hypercoagulable, Hypercoagulability, Excessive Blood Clotting, Venous Thromboembolism
Thrombophilia (sometimes called hypercoagulability or a prothrombotic state) is an abnormality of blood coagulation that increases the risk of thrombosis (blood clots in blood vessels). Such abnormalities can be identified in 50% of people who have an episode of thrombosis (such as deep vein thrombosis in the leg) that was not provoked by other causes. A significant proportion of the population has a detectable thrombophilic abnormality, but most of these develop thrombosis only in the presence of an additional risk factor.
Key facts
- Medical condition (new).name
- Thrombophilia
- Medical condition (new).image
- DVTUS.PNG
- Medical condition (new).caption
- An ultrasound image demonstrating a blood clot in the left common femoral vein.
via Wikipedia infobox
Wikidata facts
- Subclass of
- disease
Show 6 more facts
- exact match
- purl.obolibrary.org/obo/HP_0100724
- health specialty
- hematology
- NCI Thesaurus ID
- C84479
- ICD-9-CM
- 453.9
- drug or therapy used for treatment
- rivaroxaban
- on focus list of Wikimedia project
- WikiProject Medicine
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~25 min read
Encyclopedic overview
15 sectionsContents
- Signs and symptoms
- Causes
- Congenital
- Acquired
- Unclear
- Mechanism
- Diagnosis
- Screening
- Timing of Testing
- Treatment
- Prognosis
- Epidemiology
- History
- References
- External links
Thrombophilia (sometimes called hypercoagulability or a prothrombotic state) is an abnormality of blood coagulation that increases the risk of thrombosis (blood clots in blood vessels). Such abnormalities can be identified in 50% of people who have an episode of thrombosis (such as deep vein thrombosis in the leg) that was not provoked by other causes. A significant proportion of the population has a detectable thrombophilic abnormality, but most of these develop thrombosis only in the presence of an additional risk factor.
There is no specific treatment for most thrombophilias, but recurrent episodes of thrombosis may be an indication for long-term preventive anticoagulation. The first major form of thrombophilia to be identified by medical science, antithrombin deficiency, was identified in 1965, while the most common abnormalities (including factor V Leiden) were described in the 1990s.
Excerpted from Wikipedia’s “thrombophilia” article, available under the CC BY-SA 4.0 licence.