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Category

Cyclopentanes

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exo-norborneol
'''exo-Norborneol' is an alcohol containing the norbornane skeleton. Commercially available, this colorless compound may be prepared by the reaction of norbornene with formic acid, followed by hydrolysis of the resultant exo''-norbornyl formate. ==See also== Endo-Norborneol
binospirone
Binospirone (MDL-73,005-EF) is a drug which acts as a partial agonist at 5-HT1A somatodendritic autoreceptors but as an antagonist at postsynaptic 5-HT1A receptors. It has anxiolytic effects.
Oudenone
Oudenone is a molecule found in fungus metabolism. It is an inhibitor of the enzyme tyrosine hydroxylase.
abitesartan
Abitesartan (INN) is an Angiotensin II receptor antagonist.
atagabalin
Atagabalin (, ; developmental code name PD-0200390) is a drug developed by Pfizer and related to gabapentin, which similarly binds to the α2δ calcium channels (1 and 2). It was under development as a treatment for insomnia, but was discontinued following unsatisfactory trial results. The drug reached phase 2 clinical trials for this indication prior to the discontinuation of its development.
streptazolin
Streptazolin is an antibiotic and antifungal substance isolated in 1981 from Streptomyces viridochromogenes.
mepitiostane
Mepitiostane, sold under the brand name Thioderon, is an orally active antiestrogen and anabolic–androgenic steroid (AAS) of the dihydrotestosterone (DHT) group which is marketed in Japan as an antineoplastic agent for the treatment of breast cancer. It is a prodrug of epitiostanol. The drug was patented and described in 1968.
lorpiprazole
Lorpiprazole (INN; brand name Normarex) is an anxiolytic drug of the phenylpiperazine group. It has been described as a serotonin antagonist and reuptake inhibitor (SARI) in the same group as trazodone, nefazodone, and etoperidone.
decahydroxycyclopentane
Decahydroxycyclopentane is an organic compound with formula or . It is a fivefold geminal diol on a cyclopentane backbone.
azaspirodecanedione
Azaspirodecanedione is a chemical compound with the formula C9H13NO2. It is a component of the chemical structures of several of the azapirones. ==Concrete List== Alnespirone Binospirone BMY-7,378 Buspirone Gepirone (Dimethyl variation) Mdl-72832 [113777-33-6] MDL73975 [159650-30-3] MJ-7378 [21103-03-7] Ref: ORG13514 ORG12653 SNAP-8719 [255893-38-0] Patent: Tiospirone
Azaspirodecane
Azaspirodecane is a chemical compound.
eclanamine
Eclanamine (U-48,753) is a drug which was patented as an antidepressant, but was never marketed. It acts by inhibiting the reuptake of serotonin and norepinephrine.
cannabicyclol
Cannabicyclol (CBL) is a non-psychoactive cannabinoid found in Cannabis. CBL is a degradative product like cannabinol, with cannabichromene degrading into CBL through natural irradiation or under acid conditions.
endo-norborneol
'''endo-Norborneol''' is an alcohol containing the norbornane skeleton.
bevirimat
Bevirimat (research code MPC-4326) is an anti-HIV drug derived from a betulinic acid-like compound, first isolated from Syzygium claviflorum, a Chinese herb. It is believed to inhibit HIV by a novel mechanism, so-called maturation inhibition. It is not currently U.S. Food and Drug Administration (FDA) approved. It was originally developed by the pharmaceutical company Panacos and reached Phase IIb clinical trials. Myriad Genetics announced on January 21, 2009 the acquisition of all rights to bevirimat for $7M USD. On June 8, 2010 Myriad Genetics announced that it was abandoning their HIV portf
vabicaserin
Vabicaserin (codenamed SCA-136) was a novel antipsychotic and anorectic under development by Wyeth. As of 2010 it is no longer in clinical trials for the treatment of psychosis. It was also under investigation as an antidepressant but this indication appears to have been dropped as well.
capnellene
Capnellene is a naturally occurring tricyclic hydrocarbon derived from Capnella imbricata, a species of soft coral found in Indonesia. Since the 1970s, capnellene has been targeted for synthesis by numerous investigators due to its stereochemistry, functionality, and the interesting geometry of the carbon skeleton. Many alcohol derivatives of capnellene have demonstrated potential as a chemotherapeutic agent with antibacterial, anti-inflammatory and anti-tumor properties.
tedisamil
Tedisamil (3,7-dicyclopropylmethyl-9,9-tetramethylene-3,7-diazabicyclo-3,3,1-nonane) is an experimental class III antiarrhythmic agent currently being investigated for the treatment of atrial fibrillation. Tedisamil blocks multiple types of potassium channels in the heart resulting in slowed heart rate. While the effects of tedisamil have been demonstrated in both atrial and ventricular muscle, repolarization is prolonged more efficiently in the atria. Tedisamil is administered intravenously and has a half-life of approximately 8 –13 hours in circulation. Tedisamil is being developed as an alt
stemar-13-ene
Stemarene is a diterpene hydrocarbon can be produced biosynthetically through enzyme extracts from rice.
BSPP
chemical compound
ibodutant
Ibodutant was a candidate drug for irritable bowel syndrome diarrhea, developed by The Menarini Group. , it underwent a multicentre double blind efficacy clinical study. Ibodutant selectively blocks the tachykinin receptor NK2, with blockade practically complete in nanomolar concentrations. A phase 2 trial in Europe (the IRIS-2 trial) completed in May 2012 with positive results. A 52-week phase 3 study was terminated as of 2015 because of low response and negative results of study NAK-06.