Structure via PubChem · Public domain (PubChem)
binospirone
Sign in to saveBinospirone (MDL-73,005-EF) is a drug which acts as a partial agonist at 5-HT1A somatodendritic autoreceptors but as an antagonist at postsynaptic 5-HT1A receptors. It has anxiolytic effects.
Chemical data
- Formula
- C20H26N2O4
- Molecular weight
- 358.4 g/mol
- IUPAC name
- 8-[2-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)ethyl]-8-azaspiro[4.5]decane-7,9-dione
- SMILES
- C1CCC2(C1)CC(=O)N(C(=O)C2)CCNCC3COC4=CC=CC=C4O3
- InChIKey
- BVMYCHKQPGEOSI-UHFFFAOYSA-N
- XLogP
- 2.3
- Polar surface area
- 67.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 358.189
Show 3 more facts
- chemical formula
- C₂₀H₂₆N₂O₄
- canonical SMILES
- C1CCC2(C1)CC(=O)N(C(=O)C2)CCNCC3COC4=CC=CC=C4O3
- Commons category
- Binospirone
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Binospirone (MDL-73,005-EF) is a drug which acts as a partial agonist at 5-HT1A somatodendritic autoreceptors but as an antagonist at postsynaptic 5-HT1A receptors. It has anxiolytic effects.
== See also == Azapirone
Excerpted from Wikipedia’s “binospirone” article, available under the CC BY-SA 4.0 licence.