Drug safety

Thalidomide, sold under the brand names Contergan, Distaval and Thalomid among others, is an oral administered medication used to treat a number of cancers (e.g., multiple myeloma), graft-versus-host disease, and many skin disorders (e.g., complications of leprosy such as skin lesions). Thalidomide has been used to treat conditions associated with HIV: aphthous ulcers, HIV-associated wasting syndrome, diarrhea, and Kaposi's sarcoma, but increases in HIV viral load have been reported.

medicines sold directly to a consumer without a prescription from a healthcare professional, as opposed to prescription drugs, which may only be sold to consumers possessing a valid prescription

Mefloquine, sold under the brand name Lariam among others, is a medication used to prevent or treat malaria. When used for prevention it is typically started before potential exposure and continued for several weeks after potential exposure. It can be used to treat mild or moderate malaria but is not recommended for severe malaria. It is taken by mouth.

unintended effect due to administration of one or more drugs

change in the action or side effects of a drug caused by another drug

length of time that a commodity may be stored without becoming unfit for use or consumption

previously determined date after which something should no longer be used

undesired harmful effect resulting from a medication or other medical intervention

Pharmacovigilance (PV, or PhV), also known as drug safety, is the discipline within pharmaceutical science that addresses the identification, evaluation, and mitigation of adverse effects and other drug-related problems associated with pharmaceutical products.

medical condition

thumb|Polypharmacy is often defined as taking 5 or more medicines. Polypharmacy (polypragmasia) is an umbrella term to describe the simultaneous use of multiple medicines by a patient for their conditions. The term polypharmacy is often defined as regularly taking five or more medicines but there is no standard definition and the term has also been used in the context of when a person is prescribed 2 or more medications at the same time. Polypharmacy may be the consequence of having multiple long-term conditions, also known as multimorbidity and is more common in the elderly. In some cases, an

regulation designed mainly to protect the health and safety of the population, aiming at ensuring the safety, quality, and efficacy of the therapeutic goods

human disease

medical condition

method of providing drug users with uninfected equipment

medical facility

string of murders in Chicago in 1982 involving poisoned Tylenol medicine

Initiative to promote public health

adverse event caused by vaccination

mass poisonings since the 1990s

internationally agreed format for drug approvals

hospital or other institutional committees established to protect the welfare of research subjects

Human disease

Improperly prepared sulfanilamide medicine that caused mass poisoning in the US in 1937

untoward medical occurrence in human medical trials that is sufficiently serious and meeting criteria such as resulting in death, life-threatening situation, inpatient hospitalization, disability or incapacity, birth defect, or permanent impairment

United States Food and Drug Administration's Investigational New Drug (IND) program

company

Drug reaction questionnaire

EudraVigilance (European Union Drug Regulating Authorities Pharmacovigilance) is the European data processing network and management system for reporting and evaluation of suspected adverse reactions to medicines or devices which have received marketing authorisation or are actively being studied in clinical trials in the European Economic Area (EEA). The European Medicines Agency (EMA) operates the system on behalf of the European Union (EU) medicines regulatory network.

chemical indicator used for food safety and other applications

global event