Lewy body dementia

Donepezil, sold under the brand name Aricept among others, is a medication used to treat dementia of the Alzheimer's type. It appears to result in a small benefit in mental function and ability to function. Use, however, has not been shown to change the progression of the disease. Treatment should be stopped if no benefit is seen. It is taken by mouth or via a transdermal patch.

psychiatric disorder (syndrome) in which a person holds a delusion that a family member has been replaced by an identical imposter

type of progressive dementia

spherical inclusion commonly found in damaged neurons

Alpha-synuclein (aSyn) is a protein that in humans is encoded by the SNCA gene. It is a neuronal protein involved in the regulation of synaptic vesicle trafficking and the release of neurotransmitters.

American neurologist (1885–1950)

type of dementia

sleep disorder that involves abnormal behavior including the acting out of violent or dramatic dreams during the sleep phase with rapid eye movement

Spanish neurologist (1886-1971)

biographical documentary film

Synucleinopathies are neurodegenerative diseases characterised by the abnormal accumulation of aggregates of alpha-synuclein protein in neurons, nerve fibres or glial cells. The synucleinopathies include Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). Other rare disorders, such as various neuroaxonal dystrophies, also have α-synuclein pathologies.

type of dementia associated with abnormal clumps of alpha-synuclein protein in neurons

Russian neurologist (1892–1956)

Japanese psychiatrist