-Donepezil%20Structural%20Formula%20V1.svg)
donepezil
Sign in to saveDonepezil, sold under the brand name Aricept among others, is a medication used to treat dementia of the Alzheimer's type. It appears to result in a small benefit in mental function and ability to function. Use, however, has not been shown to change the progression of the disease. Treatment should be stopped if no benefit is seen. It is taken by mouth or via a transdermal patch.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 461091154
- Drug.image
- Donepezil enantiomers skeletal formulas labelled.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 350
- Drug.chirality
- Racemic mixture
- Drug.image2
- Donepezil enantiomers ball-and-stick models from xtal 2013.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 350
- Drug.USAN
- Donepezil hydrochloride
- Drug.tradename
- Aricept, others
- Drug.MedlinePlus
- a697032
- Drug.DailyMedID
- Donepezil
- Drug.pregnancy_AU
- B3
- Drug.routes_of_administration
- By mouth, transdermal
- Drug.class
- Acetylcholinesterase inhibitor
- Drug.ATC_prefix
- N06
- Drug.ATC_suffix
- DA02
via Wikipedia infobox
Article
16 sectionsContents
- Medical uses
- Alzheimer's disease
- Other
- Adverse effects
- Precautions
- Mechanism of action
- Stereochemistry
- History
- Research
- Cognitive enhancement
- ADHD
- Pervasive developmental disorder
- Anorexia nervosa
- Synergy
- References
- Further reading
Donepezil, sold under the brand name Aricept among others, is a medication used to treat dementia of the Alzheimer's type. It appears to result in a small benefit in mental function and ability to function. Use, however, has not been shown to change the progression of the disease. Treatment should be stopped if no benefit is seen. It is taken by mouth or via a transdermal patch.
Donepezil is a centrally acting reversible acetylcholinesterase inhibitor and structurally unrelated to other anticholinesterase agents. Common side effects include nausea, trouble sleeping, aggression, diarrhea, feeling tired, and muscle cramps. Serious side effects may include abnormal heart rhythms, urinary incontinence, and seizures.