Lung cancer

cancer in the lung

A carcinoid (also carcinoid tumor) is a slow-growing type of neuroendocrine tumor originating in the cells of the neuroendocrine system. In some cases, metastasis may occur. Carcinoid tumors of the midgut (jejunum, ileum, appendix, and cecum) are associated with carcinoid syndrome.

type of carcinoma that commonly arises within lung and sometime other body sites

tumor of the pulmonary apex

Osimertinib, sold under the brand name Tagrisso, is a medication used to treat non-small-cell lung carcinomas with specific mutations. It is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor.

skin carcinoma that has material basis in squamous cells

A pneumonectomy (or pneumectomy) is a surgical procedure to remove a lung. It was first successfully performed in 1933 by Dr. Evarts Graham. This is not to be confused with a lobectomy or segmentectomy, which only removes one part of the lung.

any type of epithelial lung cancer other than small-cell lung carcinoma

non-small cell lung carcinoma that derives from epithelial cells of glandular origin

lung cancer that derives from the distal bronchioles or alveoli that initially exhibit a specific non-invasive growth pattern

human disease

Disease

study (1951 to 2001) into smoking and lung cancer

lung cancer

Lurbinectedin, sold under the brand name Zepzelca, is a medication used for the treatment of small cell lung cancer.

T790M, also known as Thr790Met, is a gatekeeper mutation of the epidermal growth factor receptor (EGFR). The mutation substitutes a threonine (T) with a methionine (M) at position 790 of exon 20, affecting the ATP binding pocket of the EGFR kinase domain. Threonine is a small polar amino acid; methionine is a larger nonpolar amino acid. Rather than directly blocking inhibitor binding to the active site, T790M increases the affinity for ATP so that the inhibitors are outcompeted; irreversible covalent inhibitors such as osimertinib can overcome this resistance.

assessment of the extent to which a lung cancer has spread

pulmonary blastoma that derives from the lung or pleural cavity

surgical removal of a lobe of a lung

surgical operation