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Modification of genetic information

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retrovirus
A retrovirus is a virus that inserts a DNA copy of its RNA genome into the DNA of a host cell that it invades, thus changing the genome of that cell. After invading a host cell's cytoplasm, the virus uses its own reverse transcriptase enzyme to produce DNA from its RNA genome, the reverse of the usual pattern, thus retro (backward). The new DNA is then incorporated into the host cell genome by an integrase enzyme, at which point the retroviral DNA is referred to as a provirus. The host cell then treats the viral DNA as part of its own genome, transcribing and translating the viral genes along
transposable element
semiparasitic DNA sequence, a major fraction of eukaryotic genomes
crossing over
cellular process
genetic recombination
production of offspring with combinations of traits that differ from those found in either parent
transformation
planned genetic alteration of a cell by uptake of genetic material from the environment
horizontal gene transfer
movement of genetic material between organisms other than by transmission from parent to offspring
chromosomal translocation
phenomenon that results in unusual rearrangement of chromosomes
deletion mutation
mutation that removes a part of a DNA sequence
transduction
transfer of genetic information to a bacterium from a bacteriophage, or between bacterial or yeast cells, mediated by a phage vector
bacterial conjugation
natural genetic exchange of bacteria
gene duplication
duplication of a gene sequence within a genome
point mutation
mutation of a single gene
chromosomal inversion
reordering of genes in a DNA-sequence
homologous recombination
DNA recombination process
missense mutation
genetic point mutation that results in an amino acid change in a protein
nonsense mutation
point mutation in a sequence of DNA that results in a premature stop codon, or a nonsense codon in the transcribed mRNA, and in a truncated, incomplete, and usually nonfunctional protein product
silent mutation
point mutation where a codon is substituted with another codon that encodes the same amino acid
loss of heterozygosity
in genetics, loss of one allele at a specific locus, caused by a deletion mutation; or loss of a chromosome from a chromosome pair, resulting in abnormal hemizygosity
gene conversion
DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor
recombinase
Recombinases are genetic recombination enzymes.
paramutation
thumb|163x163px|Paramutation was first observed by the effect it had on the color of corn kernels in maize plants In epigenetics, a paramutation is an interaction between two alleles at a single locus, whereby one allele induces a heritable change in the other allele. The change may be in the pattern of DNA methylation or histone modifications. The allele inducing the change is said to be paramutagenic, while the allele that has been epigenetically altered is termed paramutable. A paramutable allele may have altered levels of gene expression, which may continue in offspring which inherit that
chromosomal rearrangement
chromosome abnormality involving a change in the structure of the native chromosome
replication-born double-strand break repair via sister chromatid exchange
repair of a replication-born double-strand DNA break in which the DNA molecule is repaired using the homologous sequence of the sister chromatid as template
fusion gene
the result of gene fusion