Category
page 1Pharmacokinetic metrics
bioavailability
In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation.
dose
quantity of something (chemical, physical, or biological) that may impact an organism biologically
clearance
rate at which a substance is removed or cleared from the body by the kidneys or in renal dialysis
onset of action
duration of time it takes for a drug's effects to come to prominence upon administration
Cmax
the peak concentration that a drug achieves in a given test area of the body
Cmin
is a term used in pharmacokinetics for the minimum blood plasma concentration reached by a drug during a dosing interval, which is the time interval between administration of two doses. This definition is slightly different from , the concentration immediately prior to administration of the next dose. is the opposite of , the maximum concentration that the drug reaches. must be above certain thresholds, such as the minimum inhibitory concentration (MIC), to achieve a therapeutic effect.