PNS neoplasia

human disease

A schwannoma (or neurilemmoma) is a usually benign nerve sheath tumor comprising Schwann cells, which normally produce the insulating myelin sheath covering peripheral nerves.

A neurofibroma is a benign nerve-sheath tumor in the peripheral nervous system. In 90% of cases, they are found as stand-alone tumors (solitary neurofibroma, solitary nerve sheath tumor or sporadic neurofibroma), while the remainder are found in persons with neurofibromatosis type I (NF1), an autosomal-dominant genetically inherited disease. They can result in a range of symptoms from physical disfiguration and pain to cognitive disability.

Human disease