Pyrrolopyrazines

thumb|1mg Dexzopiclone (Eszopiclone) tablets from China

Ranirestat (also known as AS-3201) is an aldose reductase inhibitor being developed for the treatment of diabetic neuropathy by Dainippon Sumitomo Pharma and PharmaKyorin. It has been granted orphan drug status. The drug is to be used orally.

Pirolazamide (SC-26,438) is an antiarrhythmic agent that was never marked.

Unifiram (developmental code name DM-232) is an experimental drug. that has antiamnesic and other effects in animal studies with far greater potency than piracetam. A number of related compounds are known, such as sunifiram (DM-235) and sapunifiram (MN-19). Unifiram has two enantiomers, with the dextro form being the more active isomer. It has been shown to reduce the duration of hypnosis induced by pentobarbital, without impairing motor coordination. , no formal human studies with unifiram have been conducted. Unifiram is not patented and, despite the lack of human and long-term toxicity stud