Category
page 1Telomere-binding proteins
TERT
protein-coding gene in the species Homo sapiens
POT1
Protection of telomeres protein 1 is a protein that in humans is encoded by the POT1 gene.
shelterin complex
Shelterin (also called telosome) is a protein complex known to protect telomeres in many eukaryotes from DNA repair mechanisms, as well as to regulate telomerase activity. In mammals and other vertebrates, telomeric DNA consists of repeating double-stranded 5'-TTAGGG-3' (G-strand) sequences (2-15 kilobases in humans) along with the 3'-AATCCC-5' (C-strand) complement, ending with a 50-400 nucleotide 3' (G-strand) overhang. Much of the final double-stranded portion of the telomere forms a T-loop (Telomere-loop) that is invaded by the 3' (G-strand) overhang to form a small D-l
RIF1
protein-coding gene in the species Homo sapiens
TERF2
protein-coding gene in the species Homo sapiens
ACD
protein-coding gene in the species Homo sapiens