Thiocarbonyl compounds

Mercaptopurine (6-MP), sold under the brand name Purinethol among others, is a medication used for cancer and autoimmune diseases. Specifically it is used to treat acute lymphocytic leukemia (ALL), acute promyelocytic leukemia (APL), Crohn's disease, and ulcerative colitis. For acute lymphocytic leukemia it is generally used with methotrexate. It is taken orally.

thumb|150px|right|Sodium salt of ethyl xanthate ([[sodium ethylxanthate or sodium O-ethyl dithiocarbonate)]] thumb|150px|Structure of a xanthate ester thumb|Cellulose xanthate. A xanthate is a salt or ester of a xanthic acid. The formula of the salt of xanthic acid is (where R is organyl group and M is usually Na or K). Xanthate also refers to the anion . The formula of a xanthic acid is , such as ethyl xanthic acid, while the formula of a xanthate ester is , where R and R' are organyl groups. The salts of xanthates are sometimes called O-organyl dithioates. The esters of xanthic acid are some

Thiophosgene is a red liquid with the formula . It is a molecule with trigonal planar geometry. There are two reactive C–Cl bonds that allow it to be used in diverse organic syntheses.

Dithizone is a sulfur-containing organic compound. It is a good ligand, and forms complexes with many toxic metals such as lead, thallium and mercury.

chemical compound

chemical compound

Tisopurine (or thiopurinol) is a drug used in the treatment of gout in some countries. It reduces uric acid production through inhibiting an early stage in its production.

chemical compound

Suritozole (MDL 26,479) is an investigational cognition enhancer. It acts as a partial inverse agonist at the benzodiazepine receptor site on the GABAA ion channel complex, but does not have either anxiogenic or convulsant effects, unlike other BZD inverse agonists such as DMCM. It was investigated for the treatment of depression and Alzheimer's disease in the 90s, but clinical development seems to have been discontinued.

Oltipraz is an organosulfur compound belonging to the dithiolethione class. It acts as a schistosomicide and has been shown in rodent models to inhibit the formation of cancers in the bladder, blood, colon, kidney, liver, lung, pancreas, stomach, and trachea, skin, and mammary tissue. Clinical trials of oltipraz have failed to demonstrate efficacy and have shown significant side effects, including neurotoxicity and gastrointestinal toxicity. Oltipraz has also been shown to generate superoxide radicals, which can be toxic.

chemical compound

chemical compound