Thiolanes

alt=3D space-filling model of Biotin rotating about an axis (GIF)|thumb|3D space-filling model of biotin rotating about an axis Biotin (also known as vitamin B7 and Vitamin H) is one of the B vitamins – a group of essential dietary micronutrients. Present in every living cell, it is involved as a cofactor for enzymes in numerous metabolic processes, both in humans and in other organisms, primarily related to the biochemistry of fats, carbohydrates, and amino acids.

Tetrahydrothiophene is an organosulfur compound with the formula (CH2)4S. The molecule consists of a five-membered saturated ring with four methylene groups and a sulfur atom. It is the saturated analog of thiophene and is therefore the sulfur analog of THF. It is a volatile, colorless liquid with an intensely unpleasant odor. It is also known as thiophane, thiolane, or THT.

Kadethrin is a synthetic pyrethroid with the chemical formula C23H24O4S which is used as an insecticide. It is the most potent knockdown pyrethroid (even stronger than pyrethrin II) but it is relatively unstable, especially when exposed to light (due to both the furan ring and the thiolactone group in the molecule).

Citiolone is a drug used in liver therapy.

Chloro(tetrahydrothiophene)gold(I), abbreviated (tht)AuCl, is a coordination complex of gold. Like the dimethyl sulfide analog, this compound is used as an entry point to gold chemistry. The tetrahydrothiophene ligand is labile and is readily substituted with other stronger ligands.

Bromo(tetrahydrothiophene)gold(I) is a coordination complex of gold. It is related to the more commonly used chloro(tetrahydrothiophene)gold(I). Similarly, the tetrahydrothiophene ligand is labile and is readily substituted with other stronger ligands, to give linear gold bromide complexes.