1,2-rearrangement
Sign in to saveAlso known as 1,2-migration, 1,2-shift, Whitmore 1,2-shift
A 1,2-rearrangement or 1,2-migration or 1,2-shift or Whitmore 1,2-shift is an organic reaction where a substituent moves from one atom to another atom in a chemical compound. In a 1,2 shift the movement involves two adjacent atoms but moves over larger distances are possible. In the example below the substituent R moves from carbon atom C2 to C3.
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- rearrangement reaction
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- 1,2-shift
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Encyclopedic overview
4 sectionsContents
- Reaction mechanism
- Radical 1,2-rearrangements
- 1,2-Rearrangements
- References
A 1,2-rearrangement or 1,2-migration or 1,2-shift or Whitmore 1,2-shift is an organic reaction where a substituent moves from one atom to another atom in a chemical compound. In a 1,2 shift the movement involves two adjacent atoms but moves over larger distances are possible. In the example below the substituent R moves from carbon atom C2 to C3.
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Excerpted from Wikipedia’s “1,2-rearrangement” article, available under the CC BY-SA 4.0 licence.