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I don't have sufficient context to write an accurate overview of "1453." To provide a reliable 2-sentence explanation of what it is and why it matters, I would need additional information—such as whether you're asking about a historical event, a book, a film, or something else. Could you clarify what "1453" refers to?
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May 29: The Ottoman Turks conquer Constantinople, bringing the Byzantine Empire to an end.
Year 1453 (MCDLIII) was a common year starting on Monday of the Julian calendar, the 1453rd year of the Common Era (CE) and Anno Domini (AD) designations, the 453rd year of the 2nd millennium, the 53rd year of the 15th century, and the 4th year of the 1450s decade.