2,3-epoxypropanamide
Sign in to saveAlso known as glycidamide
Glycidamide is an organic compound with the formula H2NC(O)C2H3O. It is a colorless oil. Structurally, it contains adjacent amides and epoxide functional groups. It is a bioactive, potentially toxic or even carcinogenic metabolite of acrylonitrile and acrylamide. It is a chiral molecule.
~4 min read
Encyclopedic overview
8 sectionsContents
- Structure and reactivity
- Formation
- Pathology
- Reactions
- Mechanism of action
- Metabolism
- Animal studies
- References
Glycidamide is an organic compound with the formula H2NC(O)C2H3O. It is a colorless oil. Structurally, it contains adjacent amides and epoxide functional groups. It is a bioactive, potentially toxic or even carcinogenic metabolite of acrylonitrile and acrylamide. It is a chiral molecule.
== Structure and reactivity == Glycidamide is a reactive epoxide metabolite from acrylamide and can react with nucleophiles. This results in covalent binding of the electrophile.
Excerpted from Wikipedia’s “2,3-epoxypropanamide” article, available under the CC BY-SA 4.0 licence.