ACIN1

Name

apoptotic chromatin condensation inducer 1

Type

protein-coding

Position

23,058,561–23,095,614 (−)

Aliases

ACINUS, ACN, fSAP152

Ensembl

ENSG00000100813

RefSeq RNA

NM_001164814.2, NM_001164815.2, NM_001164816.2, NM_001164817.2, NM_001386863.1

RefSeq protein

NP_001158286.2, NP_001158287.2, NP_001158288.1, NP_001158289.1, NP_001373792.1

Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011].

via MyGene.info

Gene · Ensembl

apoptotic chromatin condensation inducer 1

Symbol

ACIN1

Biotype

Protein coding

Organism

Homo sapiens

Location

14:23,058,561-23,095,614

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

via Wikidata · CC0