ACTR1B
Sign in to saveAlso known as ARP1B, CTRN2, PC3, ARP1 actin-related protein 1 homolog B, centractin beta, ARP1 actin related protein 1 homolog B, actin related protein 1B
Beta-centractin is a protein that in humans is encoded by the ACTR1B gene.
Gene data
ACTR1B- Name
- actin related protein 1B
- Type
- protein-coding
- Aliases
- ARP1B, CTRN2, PC3
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008].
via MyGene.info
Gene · Ensembl
actin related protein 1B
- Symbol
- ACTR1B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:97,655,939-97,664,114
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 101541
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10120
- genomic end
- 97664044
- genomic start
- 97655939
- chromosome
- human chromosome 2
- cytogenetic location
- 2q11.2
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Beta-centractin is a protein that in humans is encoded by the ACTR1B gene.
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins are of equal length and share 90% amino acid identity. They are present in a constant ratio of approximately 1:15 in the dynactin complex.
Excerpted from Wikipedia’s “ACTR1B” article, available under the CC BY-SA 4.0 licence.