ACTR1B
Sign in to saveAlso known as ARP1B, CTRN2, PC3, ARP1 actin-related protein 1 homolog B, centractin beta, ARP1 actin related protein 1 homolog B, actin related protein 1B
Beta-centractin is a protein that in humans is encoded by the ACTR1B gene.
Gene data
ACTR1B- Name
- actin related protein 1B
- Type
- protein-coding
- Aliases
- ARP1B, CTRN2, PC3
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 101541
- exact match
- identifiers.org/ncbigene/10120
- genomic end
- 97664044
- genomic start
- 97655939
- cytogenetic location
- 2q11.2
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Beta-centractin is a protein that in humans is encoded by the ACTR1B gene.
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins are of equal length and share 90% amino acid identity. They are present in a constant ratio of approximately 1:15 in the dynactin complex.