AGFG2
Sign in to saveAlso known as HRBL, RABR, ArfGAP with FG repeats 2
Arf-GAP domain and FG repeats-containing protein 2 is a protein that in humans is encoded by the AGFG2 gene.
Gene data
AGFG2- Name
- ArfGAP with FG repeats 2
- Type
- protein-coding
- Position
- 100,539,169–100,569,429 (+)
- Aliases
- HRBL, RABR
- Ensembl
- ENSG00000106351
- RefSeq RNA
- NM_006076.5, XM_005250306.3, XM_047420307.1, XM_047420308.1, XM_054358073.1
- RefSeq protein
- NP_006067.3, XP_005250363.1, XP_047276263.1, XP_047276264.1, XP_054214048.1
This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Feb 2013].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
ArfGAP with FG repeats 2
- Symbol
- AGFG2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:100,539,169-100,569,429
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 4430
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3268
- genomic end
- 100568220
- genomic start
- 100539203
- chromosome
- human chromosome 7
- cytogenetic location
- 7q22.1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Arf-GAP domain and FG repeats-containing protein 2 is a protein that in humans is encoded by the AGFG2 gene.
This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Excerpted from Wikipedia’s “AGFG2” article, available under the CC BY-SA 4.0 licence.