AGFG2
Sign in to saveAlso known as HRBL, RABR, ArfGAP with FG repeats 2
Arf-GAP domain and FG repeats-containing protein 2 is a protein that in humans is encoded by the AGFG2 gene.
Gene data
AGFG2- Name
- ArfGAP with FG repeats 2
- Type
- protein-coding
- Aliases
- HRBL, RABR
This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Feb 2013].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 4430
- exact match
- identifiers.org/ncbigene/3268
- genomic end
- 100568220
- genomic start
- 100539203
- cytogenetic location
- 7q22.1
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Arf-GAP domain and FG repeats-containing protein 2 is a protein that in humans is encoded by the AGFG2 gene.
This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.