Anterior gradient protein 3 homolog is a protein that in humans is encoded by the AGR3 gene.
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers. [provided by RefSeq, Dec 2016].
via MyGene.info
Anterior gradient protein 3 homolog is a protein that in humans is encoded by the AGR3 gene.
== References ==
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).