AGR3

Name

anterior gradient 3, protein disulphide isomerase family member

Type

protein-coding

Position

16,854,680–16,881,990 (−)

Aliases

AG-3, AG3, BCMP11, HAG3, PDIA18, hAG-3

Ensembl

ENSG00000173467

RefSeq RNA

NM_176813.5, XM_011515152.3, XM_047419928.1, XM_054357363.1, XM_054357364.1

RefSeq protein

NP_789783.1, XP_011513454.1, XP_047275884.1, XP_054213338.1, XP_054213339.1

This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers. [provided by RefSeq, Dec 2016].

via MyGene.info

Gene · Ensembl

anterior gradient 3, protein disulphide isomerase family member

Symbol

AGR3

Biotype

Protein coding

Organism

Homo sapiens

Location

7:16,854,680-16,881,990

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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