alanosine
Sign in to saveAlso known as L-alanosine
Alanosine (also called SDX-102) is a substance that has been studied for the treatment of pancreatic cancer. It is an antimetabolite. It is used as one of a few experimental treatments for patients with deadly pancreatic cancer when the main chemotherapeutic treatment regimen of gemcitabine is no longer useful.
Research
121 papers- Alanosine (UCSD).Current opinion in investigational drugs (London, England : 2000) · 2001
- Biosynthesis of the N-N-Bond-Containing Compound l-Alanosine.Angewandte Chemie (International ed. in English) · 2020
- The l-Alanosine Gene Cluster Encodes a Pathway for Diazeniumdiolate Biosynthesis.Chembiochem : a European journal of chemical biology · 2020
- Reductases Produce Nitric Oxide in an Alternative Pathway to Form the Diazeniumdiolate Group of l-Alanosine.Journal of the American Chemical Society · 2023
- Purine Synthesis Inhibitor L-Alanosine Impairs Mitochondrial Function and Stemness of Brain Tumor Initiating Cells.Biomedicines · 2022
via PubMed
Wikidata facts
- Mass
- 149.044
Show 4 more facts
- chemical formula
- C₃H₇N₃O₄
- isomeric SMILES
- C([C@@H](C(=O)O)N)N(N=O)O
- canonical SMILES
- C(C(C(=O)O)N)N(N=O)O
- Commons category
- L-Alanosine
Sources (2)
via Wikidata · CC0
~1 min read
Article
1 sectionsContents
- References
Alanosine (also called SDX-102) is a substance that has been studied for the treatment of pancreatic cancer. It is an antimetabolite. It is used as one of a few experimental treatments for patients with deadly pancreatic cancer when the main chemotherapeutic treatment regimen of gemcitabine is no longer useful.
== References ==
Connections
medication
Entity
infection
Entity
chemical formula
Entity
molar mass
Entity
Q180686
Entity
pancreatic cancer
Entity
CAS Registry Number
Entity
PubChem
Entity
Anatomical Therapeutic Chemical Classification System
Entity
simplified molecular input line entry specification
Entity
Q2311683
Entity
IUPAC nomenclature of chemistry
Entity
antimetabolite
Entity
International Chemical Identifier
Entity
gemcitabine
Entity
Jmol
Entity
ChEMBL
Entity
Unique Ingredient Identifier
Entity
CompTox Chemistry Dashboard
Entity