alanosine
Sign in to saveAlso known as L-alanosine
Alanosine (also called SDX-102) is a substance that has been studied for the treatment of pancreatic cancer. It is an antimetabolite. It is used as one of a few experimental treatments for patients with deadly pancreatic cancer when the main chemotherapeutic treatment regimen of gemcitabine is no longer useful.
Research
121 papers- Alanosine (UCSD).Current opinion in investigational drugs (London, England : 2000) · 2001
- Biosynthesis of the N-N-Bond-Containing Compound l-Alanosine.Angewandte Chemie (International ed. in English) · 2020
- The l-Alanosine Gene Cluster Encodes a Pathway for Diazeniumdiolate Biosynthesis.Chembiochem : a European journal of chemical biology · 2020
- Reductases Produce Nitric Oxide in an Alternative Pathway to Form the Diazeniumdiolate Group of l-Alanosine.Journal of the American Chemical Society · 2023
- Purine Synthesis Inhibitor L-Alanosine Impairs Mitochondrial Function and Stemness of Brain Tumor Initiating Cells.Biomedicines · 2022
via PubMed
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Encyclopedic overview
1 sectionsContents
- References
Alanosine (also called SDX-102) is a substance that has been studied for the treatment of pancreatic cancer. It is an antimetabolite. It is used as one of a few experimental treatments for patients with deadly pancreatic cancer when the main chemotherapeutic treatment regimen of gemcitabine is no longer useful.
== References ==
Excerpted from Wikipedia’s “alanosine” article, available under the CC BY-SA 4.0 licence.