AMBP

Also known as A1M, EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC

protein-coding gene in the species Homo sapiens

Gene data

AMBP

Name: alpha-1-microglobulin/bikunin precursor
Type: protein-coding
Position: 114,060,127–114,080,970 (−)
Aliases: A1M, EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI
Ensembl: ENSG00000106927
RefSeq RNA: NM_001633.4
RefSeq protein: NP_001624.1

This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008].