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ankylosing spondylitis

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ankylosing spondylitis

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Also known as Bechterew's disease, Marie-Strümpell disease, Bekhterev syndrome, Bekhterev's disease, Marie-Strumpell disease, Spondylarthritis ankylopoietica, ankylosing spondylarthritis, ankylosing spondylarthritides

type of arthritis in which there is long term inflammation of the joints of the spine

OverviewAI-generated

Ankylosing spondylitis is a medical condition described by the NHS. It is classified under the ICD-9-CM code 720.0 and the ICPC 2 code L88. The condition is also associated with the NCI Thesaurus ID C84564.

The subject has 16,248 social media followers. It is referenced by 398 other encyclopedia articles. A search for the term yields 24,403 results in PubMed.

Synthesized by Vinony from 16 facts across 4 sources: Wikidata, Firecrawl, PubMed, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.

Research

24,403 papers

via PubMed

Described at

Ankylosing spondylitis - NHS

Read about ankylosing spondylitis (AS) and other types of axial spondyloarthritis, a long-term (chronic) condition in which the spine and other areas of the body become inflamed.

nhs.uk

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Encyclopedic overview

Ankylosing spondylitis (AS) is a type of arthritis from the disease spectrum of axial spondyloarthritis. The term comes from the Greek ankylos meaning crooked, curved or rounded, spondylos meaning vertebra, and -itis meaning inflammation. It is characterized by long-term inflammation of the joints of the spine, typically where the spine joins the pelvis. Lower back pain is a hallmark, but eye and gastrointestinal problems and arthritis of other joints may also occur. Joint mobility in the affected areas often worsens over time, though the progression of symptoms varies significantly.

Ankylosing spondylitis is believed to involve a combination of genetic and environmental factors. More than 90% of people affected in the UK have a specific human leukocyte antigen known as the HLA-B27 antigen, though the genetic correlation varies across populations (e.g., only 70% of AS patients in Turkey are HLA-B27 positive). The underlying mechanism is believed to be autoimmune or autoinflammatory. Diagnosis is based on symptoms with support from medical imaging and blood tests. AS is a type of seronegative spondyloarthropathy, meaning that tests show no presence of rheumatoid factor (RF) antibodies.

Excerpted from Wikipedia’s “ankylosing spondylitis” article, available under the CC BY-SA 4.0 licence.

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