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annonacin

Structure via PubChem · Public domain (PubChem)

EntityQ2058866· pop 11· linked from 10 articles

Annonacin is a chemical compound with toxic effects on neurons in vitro. It is found in some fruits, such as the paw paw, custard apples, soursop, and others from the family Annonaceae. It is a member of the class of compounds known as acetogenins. Annonacin-containing fruit products are regularly consumed throughout the Caribbean for their traditional medicine uses.

Chemical data

Formula
C35H64O7
Molecular weight
596.9 g/mol
IUPAC name
(2S)-2-methyl-4-[(2R,8R,13R)-2,8,13-trihydroxy-13-[(2R,5R)-5-[(1R)-1-hydroxytridecyl]oxolan-2-yl]tridecyl]-2H-furan-5-one

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

~3 min read

Encyclopedic overview

3 sections
Contents
  • Traditional medicine
  • Neurotoxicity
  • References

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Annonacin is a chemical compound with toxic effects on neurons in vitro. It is found in some fruits, such as the paw paw, custard apples, soursop, and others from the family Annonaceae. It is a member of the class of compounds known as acetogenins. Annonacin-containing fruit products are regularly consumed throughout the Caribbean for their traditional medicine uses.

Excerpted from Wikipedia’s “annonacin” article, available under the CC BY-SA 4.0 licence.

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