APLP1

Name

amyloid beta precursor like protein 1

Type

protein-coding

Position

35,867,899–35,879,803 (+)

Aliases

APLP

Ensembl

ENSG00000105290

RefSeq RNA

NM_001024807.3, NM_005166.5, XM_017026737.3, XM_017026738.3, XM_054320812.1

RefSeq protein

NP_001019978.1, NP_005157.1, XP_016882226.1, XP_016882227.1, XP_054176787.1

This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

amyloid beta precursor like protein 1

Symbol

APLP1

Biotype

Protein coding

Organism

Homo sapiens

Location

19:35,867,899-35,879,803

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

3qmk.png

via Wikidata · CC0