ARF5
Sign in to saveAlso known as ADP ribosylation factor 5
ADP-ribosylation factor 5 is a protein that in humans is encoded by the ARF5 gene.
Gene data
ARF5- Name
- ARF GTPase 5
- Type
- protein-coding
This gene is a member of the human ADP-ribosylation factor (ARF) gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization. [provided by RefSeq, Dec 2010].
via MyGene.info
Wikidata facts
- Image
- PDB 2b6h EBI.jpg
Show 5 more facts
- exact match
- identifiers.org/ncbigene/381
- HomoloGene ID
- 129625
- genomic end
- 127591700
- genomic start
- 127588386
- cytogenetic location
- 7q32.1
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ADP-ribosylation factor 5 is a protein that in humans is encoded by the ARF5 gene.
ADP-ribosylation factor 5 (ARF5) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization. The ARF5 gene spans approximately 3.2kb of genomic DNA and contains six exons and five introns.