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GeneQ18039841· pop 7· linked from 4 articles

Also known as ASEF, ASEF1, GEF4, STM6, Rho guanine nucleotide exchange factor 4, SMIM39

Rho guanine nucleotide exchange factor 4 is a protein that in humans is encoded by the ARHGEF4 gene.

Gene data

ARHGEF4
Name
Rho guanine nucleotide exchange factor 4
Type
protein-coding
Aliases
ASEF, ASEF1, GEF4, STM6

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by this gene may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jun 2013].

via MyGene.info

Gene · Ensembl

Rho guanine nucleotide exchange factor 4

Symbol
ARHGEF4
Biotype
Protein coding
Organism
Homo sapiens
Location
2:130,836,864-131,047,263
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
Protein ARHGEF4 PDB 2dx1.png
Show 5 more facts
HomoloGene ID
49414
genomic start
130836914
genomic end
131804836
cytogenetic location
2q21.1
Sources (3)

via Wikidata · CC0

~1 min read

Article

5 sections
Contents
  • Function
  • Interactions
  • References
  • External links
  • Further reading

Rho guanine nucleotide exchange factor 4 is a protein that in humans is encoded by the ARHGEF4 gene.

== Function ==

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via Wikidata sitelinks · CC0

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