ARHGEF4
Sign in to saveAlso known as ASEF, ASEF1, GEF4, STM6, Rho guanine nucleotide exchange factor 4, SMIM39
Rho guanine nucleotide exchange factor 4 is a protein that in humans is encoded by the ARHGEF4 gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to ARHGEF4, and connects out to Q180686, human chromosome 2 and Ensembl genome database project.
It is catalogued under topics including Genes mutated in mice and Genes on human chromosome 2.
Vinony links it to 6 Wikipedia language editions.
Gene data
ARHGEF4- Name
- Rho guanine nucleotide exchange factor 4
- Type
- protein-coding
- Aliases
- ASEF, ASEF1, GEF4, STM6
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by this gene may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jun 2013].
via MyGene.info
Gene · Ensembl
Rho guanine nucleotide exchange factor 4
- Symbol
- ARHGEF4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:130,836,864-131,047,263
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein ARHGEF4 PDB 2dx1.png
Show 5 more facts
- HomoloGene ID
- 49414
- exact match
- identifiers.org/ncbigene/50649
- genomic start
- 130836914
- genomic end
- 131804836
- cytogenetic location
- 2q21.1
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- References
- External links
- Further reading
Rho guanine nucleotide exchange factor 4 is a protein that in humans is encoded by the ARHGEF4 gene.
== Function ==
Excerpted from Wikipedia’s “ARHGEF4” article, available under the CC BY-SA 4.0 licence.