ARHGEF5
Sign in to saveAlso known as GEF5, P60, TIM, TIM1, Rho guanine nucleotide exchange factor 5
Rho guanine nucleotide exchange factor 5 is a protein that in humans is encoded by the ARHGEF5 gene.
Gene data
ARHGEF5- Name
- Rho guanine nucleotide exchange factor 5
- Type
- protein-coding
- Position
- 144,355,288–144,380,632 (+)
- Aliases
- GEF5, P60, TIM, TIM1
- Ensembl
- ENSG00000050327
- RefSeq RNA
- NM_001002861.1, NM_005435.4, XM_017012623.3, XM_054359021.1
- RefSeq protein
- NP_005426.2, XP_016868112.1, XP_054214996.1
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
Rho guanine nucleotide exchange factor 5
- Symbol
- ARHGEF5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:144,355,288-144,380,632
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 66300
- exact match
- identifiers.org/ncbigene/7984
- genomic start
- 144052381
- genomic end
- 144077725
- cytogenetic location
- 7q35
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- References
- External links
- Further reading
Rho guanine nucleotide exchange factor 5 is a protein that in humans is encoded by the ARHGEF5 gene.
Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.