ARID4B
Sign in to saveAlso known as BCAA, BRCAA1, RBBP1L1, RBP1L1, SAP180, AT-rich interaction domain 4B
AT-rich interactive domain-containing protein 4B is a protein that in humans is encoded by the ARID4B gene.
Gene data
ARID4B- Name
- AT-rich interaction domain 4B
- Type
- protein-coding
- Position
- 235,131,634–235,328,800 (−)
- Aliases
- BCAA, BRCAA1, RBBP1L1, RBP1L1, SAP180
- Ensembl
- ENSG00000054267
- RefSeq RNA
- NM_001206794.2, NM_016374.6, NM_031371.4, NR_135074.2, XM_006711781.4
- RefSeq protein
- NP_001193723.1, NP_057458.4, NP_112739.2, XP_006711844.1, XP_011542514.1
This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
AT-rich interaction domain 4B
- Symbol
- ARID4B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:235,131,634-235,328,800
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 12847
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/51742
- genomic end
- 235491534
- genomic start
- 235294949
- chromosome
- human chromosome 1
- cytogenetic location
- 1q42.3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- References
- External links
- Further reading
AT-rich interactive domain-containing protein 4B is a protein that in humans is encoded by the ARID4B gene.
== Function ==
Excerpted from Wikipedia’s “ARID4B” article, available under the CC BY-SA 4.0 licence.