ARL1

Name

ARF like GTPase 1

Type

protein-coding

Position

101,393,116–101,407,772 (−)

Aliases

ARFL1

Ensembl

ENSG00000120805

RefSeq RNA

NM_001177.6, NM_001301068.1

RefSeq protein

NP_001168.1, NP_001287997.1

The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014].

via MyGene.info

Gene · Ensembl

ARF like GTPase 1

Symbol

ARL1

Biotype

Protein coding

Organism

Homo sapiens

Location

12:101,365,309-101,407,794

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein ARL1 PDB 1r4a.png

via Wikidata · CC0