arsphenamine

Also known as Salvarsan, arsenphenolamine hydrochloride, 4,4'-arsenobis(2-aminophenol) dihydrochloride, 3,3'-diamino-4,4'-dihydroxyarsenobenzene dihydrochloride, Ehrlich 606, 4,4'-(diarsene-1,2-diyl)bis(2-aminophenol) dihydrochloride, 4,4'-(1,2-diarsenediyl)bis(2-aminophenol) dihydrochloride

Chemical data

Formula: C12H14As2Cl2N2O2
Molecular weight: 439 g/mol
IUPAC name: [5-(3-azaniumyl-4-hydroxyphenyl)arsanylidenearsanyl-2-hydroxyphenyl]azanium dichloride
SMILES: C1=CC(=C(C=C1[As]=[As]C2=CC(=C(C=C2)O)[NH3+])[NH3+])O.[Cl-].[Cl-]
InChIKey: VLAXZGHHBIJLAD-UHFFFAOYSA-N
Polar surface area: 95.7 Å²
H-bond donors: 4
H-bond acceptors: 4
Formal charge: 0

via PubChem

Research

543 papers

Arsphenamine encephalopathy.

~4 min read

Article

4 sections

Contents

History
Structure
See also
References

thumb|right|300px|The structure of arsphenamine has been proposed to be akin to azobenzene (A). Salvarsan is now assumed to be a mixture of the trimer (B) and the pentamer (C).

Arsphenamine, also known as Salvarsan or compound 606, is an antibiotic drug that was introduced at the beginning of the 1910s as the first effective treatment for the deadly infectious diseases syphilis, relapsing fever, and African trypanosomiasis. This organoarsenic compound was the first modern antimicrobial agent.