ASB1

Also known as ASB-1, ankyrin repeat and SOCS box containing 1

Ankyrin repeat and SOCS box protein 1 is a protein that is in humans, encoded by the ASB1 gene.

In the Vinony graph

Vinony's link graph records 4 inbound references to ASB1, and connects out to PubMed, human chromosome 2 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 2.

Vinony links it to 5 Wikipedia language editions.

Gene data

ASB1

Name: ankyrin repeat and SOCS box containing 1
Type: protein-coding
Position: 238,426,742–238,452,250 (+)
Aliases: ASB-1
Ensembl: ENSG00000065802
RefSeq RNA: NM_001040445.3, NM_001330196.2, NM_016114.3
RefSeq protein: NP_001035535.1, NP_001317125.1

The protein encoded by this gene contains an ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, targeting them for ubiquitination and degradation. [provided by RefSeq, Aug 2016].

Gene Ontology

Biological process

negative regulation of cytokine production protein ubiquitination protein ubiquitination intracellular signal transduction proteasome-mediated ubiquitin-dependent protein catabolic process

Molecular function

protein binding ubiquitin protein ligase activity ubiquitin-like ligase-substrate adaptor activity

Cellular component

ubiquitin ligase complex ubiquitin ligase complex cytoplasm cytoplasm cytosol cytosol

Pathways

Adaptive Immune System Immune System Metabolism of proteins Post-translational protein modification Neddylation Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation

via MyGene.info

Gene · Ensembl

ankyrin repeat and SOCS box containing 1

Symbol: ASB1
Biotype: Protein coding
Organism: Homo sapiens
Location: 2:238,426,742-238,452,250
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 9390
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/51665
genomic end: 239360891
genomic start: 239335383
chromosome: human chromosome 2
cytogenetic location: 2q37.3
expressed in: caudate nucleus

Sources (4)

via Wikidata · CC0

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Encyclopedic overview

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Contents

References
External links
Further reading

Ankyrin repeat and SOCS box protein 1 is a protein that is in humans, encoded by the ASB1 gene.

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation.

Excerpted from Wikipedia’s “ASB1” article, available under the CC BY-SA 4.0 licence.