File:Blausen_0257_CoronaryArtery_Plaque.png · Wikimedia Commons · See Wikimedia Commons
atherosclerosis
Sign in to saveAlso known as arteriosclerotic vascular disease, ASVD, atheromatous plaque
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AI-generated from the Wikipedia summary — may contain errors.
Key facts
- Medical condition.name
- Atherosclerosis
- Medical condition.synonyms
- Arteriosclerotic vascular disease (ASVD)
- Medical condition.image
- Blausen 0257 CoronaryArtery Plaque.png
- Medical condition.caption
- Illustration depicting atherosclerosis in a coronary artery
- Medical condition.field
- Cardiology, vascular surgery, cardiothoracic surgery, interventional radiology
- Medical condition.symptoms
- None
- Medical condition.complications
- Coronary artery disease, stroke, peripheral artery disease, kidney problems, heart disease
- Medical condition.onset
- Youth (worsens with age)
- Medical condition.causes
- Accumulation of saturated fats, smoking, high blood pressure, and diabetes
- Medical condition.risks
- High blood pressure, diabetes, smoking, obesity, family history, unhealthy diet (notably trans fat and hydrogenated oils), chronic Vitamin C deficiency
- Medical condition.prevention
- Healthy diet, exercise, not smoking, maintaining a normal weight
- Medical condition.medication
- Statins, blood pressure medication, aspirin
- Medical condition.frequency
- ≈100% (>65 years old)
via Wikipedia infobox
Research
198,415 papers- Atherosclerosis: Known and unknown.ReviewPathology international · 2022Fan J, Watanabe TDOI: 10.1111/pin.13202
- The changing landscape of atherosclerosis.ReviewNature · 2021Libby PDOI: 10.1038/s41586-021-03392-8
- Research Progress on the Relationship between Atherosclerosis and Inflammation.ReviewBiomolecules · 2018Zhu Y, Xian X, Wang Z et al.DOI: 10.3390/biom8030080
- Atherosclerosis.ReviewCirculation research · 2018Kobiyama K, Ley KDOI: 10.1161/CIRCRESAHA.118.313816
- LDL cholesterol as a causal agent of atherosclerosis.ReviewClinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis · 2024Pedro-Botet J, Climent E, Benaiges DDOI: 10.1016/j.arteri.2024.07.001
- Small rodent models of atherosclerosis.ReviewBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2020Zhao Y, Qu H, Wang Y et al.DOI: 10.1016/j.biopha.2020.110426
- Progress and challenges in translating the biology of atherosclerosis.ReviewNature · 2011Libby P, Ridker PM, Hansson GKDOI: 10.1038/nature10146
- The immune system in atherosclerosis.ReviewNature immunology · 2011Hansson GK, Hermansson ADOI: 10.1038/ni.2001
via PubMed
Wikidata facts
- Image
- Endothelial dysfunction Atherosclerosis.png
Show 4 more facts
- Commons category
- Atherosclerosis
- NCI Thesaurus ID
- C35771
- exact match
- identifiers.org/doid/DOID:1936
- ICD-9-CM
- 440
Sources (12)
via Wikidata · CC0
~42 min read
Article
34 sectionsContents
- Signs and symptoms
- Risk factors
- Modifiable
- Nonmodifiable
- Lesser or uncertain
- Dietary
- Cellular
- Calcification and lipids
- Visible features
- Rupture and stenosis
- Accelerated growth of plaques
- Components
- Diagnosis
- Prevention
- Diet
- Exercise
- Treatment
- Statins
- Surgery
- Other
- Epidemiology
- Etymology
- Economics
- Research
- Lipids
- miRNA
- DNA damage
- Microorganisms
- Vascular smooth muscle cells
- Treatment research
- Presence in other species
- Notes
- References
- External links
Atherosclerosis is a pattern of the disease arteriosclerosis, characterized by development of abnormalities called lesions in walls of arteries. This is a chronic inflammatory disease involving many different cell types and is driven by elevated blood levels of cholesterol. These lesions may lead to narrowing of the arterial walls due to buildup of atheromatous plaques.
At the onset, there are usually no symptoms, but if they develop, symptoms generally begin around middle age. In severe cases, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney disorders, depending on the body part(s) in which the affected arteries are located.