ATP5F1B
Sign in to saveAlso known as ATPMB, ATPSB, HEL-S-271, ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide, ATP synthase F1 subunit beta, ATP5B
ATP synthase F1 subunit beta, mitochondrial is an enzyme that in humans is encoded by the ATP5F1B gene.
Gene data
ATP5F1B- Name
- ATP synthase F1 subunit beta
- Type
- protein-coding
- Position
- 56,637,490–56,646,079 (−)
- Aliases
- ATP5B, ATPMB, ATPSB, DYT38, HEL-S-271, HUMOP2
- Ensembl
- ENSG00000110955
- RefSeq RNA
- NM_001686.4
- RefSeq protein
- NP_001677.2
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
ATP synthase F1 subunit beta
- Symbol
- ATP5F1B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:56,637,490-56,646,079
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- ATP5B within Bos taurus mitochondrial ATP synthase state 1a - 5ARA.png
Show 8 more facts
- HomoloGene ID
- 1273
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/506
- genomic end
- 56645984
- genomic start
- 57031959
- chromosome
- human chromosome 12
- cytogenetic location
- 12q13.3
- expressed in
- gastrocnemius muscle
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- References
- External links
- Further reading
ATP synthase F1 subunit beta, mitochondrial is an enzyme that in humans is encoded by the ATP5F1B gene.
== Function ==
Excerpted from Wikipedia’s “ATP5F1B” article, available under the CC BY-SA 4.0 licence.