Structure via PubChem · Public domain (PubChem)
Chemical data
- Formula
- C19H21NO4
- Molecular weight
- 327.4 g/mol
- IUPAC name
- (6aS)-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol
- SMILES
- CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=CC(=C(C=C43)OC)O)OC)O
- InChIKey
- LZJRNLRASBVRRX-ZDUSSCGKSA-N
- XLogP
- 2.7
- Polar surface area
- 62.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
263 papers- Boldine: a narrative review of the bioactive compound with versatile biological and pharmacological potential.Journal of complementary & integrative medicine · 2024
- Pharmacology of boldine: summary of the field and update on recent advances.Frontiers in pharmacology · 2024
- Semisynthetic Transformations on (+)-Boldine Reveal a 5-HT(2A/2C)R Antagonist.Journal of natural products · 2022
- Boldine Ameliorates Vascular Oxidative Stress and Endothelial Dysfunction: Therapeutic Implication for Hypertension and Diabetes.Journal of cardiovascular pharmacology · 2015
- Boldine and its antioxidant or health-promoting properties.Chemico-biological interactions · 2006
via PubMed
Wikidata facts
- Subclass of
- aporphine alkaloids
- Mass
- 327.147
Show 3 more facts
- chemical formula
- C₁₉H₂₁NO₄
- canonical SMILES
- CN1CCC2=CC(=C(C3=C2C1CC4=CC(=C(C=C43)OC)O)OC)O
- isomeric SMILES
- CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=CC(=C(C=C43)OC)O)OC)O
Sources (2)
via Wikidata · CC0
Article · Italiano
La boldina è un alcaloide estratto dalle foglie del Peumus boldus (Monimiaceae) e presente anche nella Lindera aggregata. La boldina pura cristallizzata provoca un aumento della secrezione biliare superiore di cinque volte al volume secreto normalmente. Esplica un'intensa azione ipotensiva nel cane vagotomizzato.
Abstract from DBpedia / Wikipedia · CC BY-SA