BRAT1

Name

BRCA1 associated ATM activator 1

Type

protein-coding

Position

2,537,784–2,555,782 (−)

Aliases

BAAT1, C7orf27, NEDCAS, RMFSL

Ensembl

ENSG00000106009

RefSeq RNA

NM_001350626.2, NM_001350627.2, NM_001445561.1, NM_001445562.1, NM_001445563.1

RefSeq protein

NP_001337555.1, NP_001337556.1, NP_001432490.1, NP_001432491.1, NP_001432492.1

The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012].

via MyGene.info

Gene · Ensembl

BRCA1 associated ATM activator 1

Symbol

BRAT1

Biotype

Protein coding

Organism

Homo sapiens

Location

7:2,537,784-2,555,782

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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