BRD7
Sign in to saveAlso known as BP75, CELTIX1, NAG4, bromodomain containing 7, SMARCI1
Gen der Spezies Homo sapiens
Gene data
BRD7- Name
- bromodomain containing 7
- Type
- protein-coding
- Position
- 50,313,487–50,369,059 (−)
- Aliases
- BP75, CELTIX1, NAG4, SMARCI1
- Ensembl
- ENSG00000166164
- RefSeq RNA
- NM_001173984.4, NM_001437990.1, NM_001438173.1, NM_001438174.1, NM_001438175.1
- RefSeq protein
- NP_001167455.1, NP_001424919.1, NP_001425102.1, NP_001425103.1, NP_001425104.1
This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010].
Gene Ontology
Biological process
chromatin remodelingregulation of transcription by RNA polymerase IIregulation of transcription by RNA polymerase IIregulation of transcription by RNA polymerase IIregulation of mitotic cell cycleregulation of mitotic metaphase/anaphase transitionpositive regulation of T cell differentiationpositive regulation of cell differentiation
Molecular function
Pathways
Hepatocellular carcinoma - Homo sapiens (human)Generic Transcription PathwayTranscriptional Regulation by TP53Chromatin organizationRegulation of TP53 ActivityRegulation of TP53 Activity through AcetylationRNA Polymerase II TranscriptionGene expression (Transcription)ATP-dependent chromatin remodelersSWI/SNF chromatin remodelers
via MyGene.info
Gene · Ensembl
bromodomain containing 7
- Symbol
- BRD7
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:50,313,487-50,369,059
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 8085
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/29117
- genomic end
- 50368988
- genomic start
- 50347398
- chromosome
- human chromosome 16
- cytogenetic location
- 16q12.1
- expressed in
- popliteal artery
Sources (4)
via Wikidata · CC0