C1QBP
Sign in to saveAlso known as GC1QBP, HABP1, SF2p32, gC1Q-R, gC1qR, p32, complement component 1, q subcomponent binding protein, complement C1q binding protein
Complement component 1 Q subcomponent-binding protein, mitochondrial is a protein that in humans is encoded by the C1QBP gene.
Gene data
C1QBP- Name
- complement C1q binding protein
- Type
- protein-coding
- Position
- 5,432,625–5,448,830 (−)
- Aliases
- COXPD33, GC1QBP, HABP1, SF2AP32, SF2p32, gC1Q-R, gC1qR, p32
- Ensembl
- ENSG00000108561
- RefSeq RNA
- NM_001212.4
- RefSeq protein
- NP_001203.1
The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
complement C1q binding protein
- Symbol
- C1QBP
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:5,432,625-5,448,830
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~2 min read
Encyclopedic overview
6 sectionsContents
- Protein subunit
- Protein structure
- Interactions
- References
- Further reading
- External links
Complement component 1 Q subcomponent-binding protein, mitochondrial is a protein that in humans is encoded by the C1QBP gene.
The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein.
Excerpted from Wikipedia’s “C1QBP” article, available under the CC BY-SA 4.0 licence.