C20orf27
Sign in to saveAlso known as chromosome 20 open reading frame 27
UPF0687 protein C20orf27 is a protein that in humans is encoded by the C20orf27 gene. It is expressed in the majority of the human tissues. One study on this protein revealed its role in regulating cell cycle, apoptosis, and tumorigenesis via promoting the activation of NFĸB pathway.
Gene data
ADISSP- Name
- adipose secreted signaling protein
- Type
- protein-coding
- Position
- 3,751,220–3,768,738 (−)
- Aliases
- C20orf27
- Ensembl
- ENSG00000101220
- RefSeq RNA
- NM_001039140.3, NM_001258429.2, NM_001258430.2, NM_017874.2, NR_047675.2
- RefSeq protein
- NP_001034229.1, NP_001245358.1, NP_001245359.1, XP_011527568.1, XP_047296201.1
Enables protein phosphatase 1 binding activity. Involved in positive regulation of NIK/NF-kappaB signaling and positive regulation of transforming growth factor beta receptor signaling pathway. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
adipose secreted signaling protein
- Symbol
- ADISSP
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:3,751,220-3,768,738
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 41660
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/54976
- genomic end
- 3767781
- Commons category
- C20orf27
- genomic start
- 3734155
- chromosome
- human chromosome 20
- cytogenetic location
- 20p13
- expressed in
- monocyte
Sources (4)
via Wikidata · CC0
~13 min read
Encyclopedic overview
21 sectionsContents
- Gene
- Transcription
- Known isoforms
- Proteins
- Physical features
- Post-translation modifications
- Structure
- Subcellular Localization
- Expression
- Regulation of expression
- Gene level expression
- Transcript level regulation
- Function and clinical significance
- Interacting proteins
- Clinical significance
- Homology and evolution history
- Paralogs
- Orthologs
- References
- External links
- Further reading
UPF0687 protein C20orf27 is a protein that in humans is encoded by the C20orf27 gene. It is expressed in the majority of the human tissues. One study on this protein revealed its role in regulating cell cycle, apoptosis, and tumorigenesis via promoting the activation of NFĸB pathway.
== Gene == The UPF0687 Protein C20orf27 has four other aliases, Chromosome 20 Open Reading Frame 27, Hypothetical Protein LOC54976, C20orf27, and FLJ20550. It is located on the minus strand at 20p13. It consists of 7 exons and 12 introns. This most updated annotation shows that gene C20orf27 starts at 3,753,499 bp to 3,768,388 bp on Chromosome 20.
Excerpted from Wikipedia’s “C20orf27” article, available under the CC BY-SA 4.0 licence.