C6orf58 is a human gene located at locus 6q22.33 of chromosome 6 and encodes for UPF0762, a protein which is subsequently secreted after cleavage of a signal peptide. DUF781, which is the singular identifiable domain in UPF0762, is tied to liver development in an orthologous protein in zebrafish. The function of the human UPF0762 is not yet well characterized.
Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
via Wikidata · CC0
C6orf58 is a human gene located at locus 6q22.33 of chromosome 6 and encodes for UPF0762, a protein which is subsequently secreted after cleavage of a signal peptide. DUF781, which is the singular identifiable domain in UPF0762, is tied to liver development in an orthologous protein in zebrafish. The function of the human UPF0762 is not yet well characterized.
==Gene and mRNA== {| class="wikitable" |- ! Genomic DNA Length (base pairs) !! Exons !! Mature mRNA Length (base pairs) !! Splice variants !! Signal peptide CDS (base pair) !! Mature Peptide CDS (base pair) !! 5'-UTR (base pair) !! 3'-UTR (base pair) |- | 14644 || 6 || 1200 || 3 || 13-72 || 73-1002 || 1-12 || 1003-1200 |}
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).