CABYR
Sign in to saveAlso known as CABYRa, CABYRc, CABYRc/d, CABYRe, CBP86, CT88, FSP-2, FSP2
Calcium-binding tyrosine phosphorylation-regulated protein is a protein that in humans is encoded by the CABYR gene.
Gene data
CABYR- Name
- calcium binding tyrosine phosphorylation regulated
- Type
- protein-coding
- Position
- 24,138,961–24,161,603 (+)
- Aliases
- CABYRa, CABYRc, CABYRc/d, CABYRe, CBP86, CT88, FSP-2, FSP2
- Ensembl
- ENSG00000154040
- RefSeq RNA
- NM_001308231.2, NM_012189.4, NM_138643.3, NM_138644.3, NM_153768.3
- RefSeq protein
- NP_001295160.1, NP_036321.2, NP_619584.1, NP_619585.1, NP_722452.1
To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3 has been identified for this gene. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2013].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
calcium binding tyrosine phosphorylation regulated
- Symbol
- CABYR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 18:24,138,961-24,161,603
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 49299
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/26256
- genomic end
- 24161600
- genomic start
- 24138987
- chromosome
- human chromosome 18
- cytogenetic location
- 18q11.2
- expressed in
- testicle
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Calcium-binding tyrosine phosphorylation-regulated protein is a protein that in humans is encoded by the CABYR gene.
To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3 has been identified for this gene. Transcript variants of this gene encode multiple protein isoforms. An additional transcript and isoform has not been fully characterized.
Excerpted from Wikipedia’s “CABYR” article, available under the CC BY-SA 4.0 licence.