Cas scaffolding protein family member 4 is a protein that in humans is encoded by the CASS4 gene.
Cas scaffolding protein family member 4 is a protein that in humans is encoded by the CASS4 gene.
== History and discovery == CASS4 (Crk associated substrate 4) is the fourth and last described member of the CAS protein family. CASS4 was detected by Singh et al. in 2008 following in silico screening of databases describing expressed sequence tags from an evolutionarily diverse group of organisms, using the CAS-related proteins (p130Cas, NEDD9/HEF1 and EFS) mRNAs as templates. Singh et al. subsequently cloned and characterized the CASS4 gene, originally assigning the name HEPL (HEF1-EFS-p130Cas-like) for similarity to the other three defined CAS genes. The official name was subsequently changed to CASS4 by the Human Genome Organization (HUGO) Gene Nomenclature Committee (HGNC).
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).