Gene data
CDC23- Name
- cell division cycle 23
- Type
- protein-coding
- Position
- 138,180,663–138,213,346 (−)
- Aliases
- ANAPC8, APC8, CUT23
- Ensembl
- ENSG00000094880
- RefSeq RNA
- NM_004661.4
- RefSeq protein
- NP_004652.2
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cell division cycle 23
- Symbol
- CDC23
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:138,180,663-138,213,346
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 3426
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8697
- genomic end
- 137549032
- genomic start
- 138187650
- chromosome
- human chromosome 5
- cytogenetic location
- 5q31.2
Sources (4)
via Wikidata · CC0