CDC42EP4
Sign in to saveAlso known as BORG4, CEP4, KAIA1777, CDC42 effector protein 4
Cdc42 effector protein 4 is a protein that in humans is encoded by the CDC42EP4 gene.
Gene data
CDC42EP4- Name
- CDC42 effector protein 4
- Type
- protein-coding
- Position
- 73,281,331–73,312,005 (−)
- Aliases
- BORG4, CEP4, KAIA1777
- Ensembl
- ENSG00000179604
- RefSeq RNA
- NM_012121.5, XM_005257182.3, XM_054315635.1
- RefSeq protein
- NP_036253.2, XP_005257239.1, XP_054171610.1
The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
CDC42 effector protein 4
- Symbol
- CDC42EP4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:73,281,331-73,312,005
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 8110
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/23580
- genomic end
- 73312005
- genomic start
- 71279763
- chromosome
- human chromosome 17
- cytogenetic location
- 17q25.1
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Cdc42 effector protein 4 is a protein that in humans is encoded by the CDC42EP4 gene.
The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.
Excerpted from Wikipedia’s “CDC42EP4” article, available under the CC BY-SA 4.0 licence.