Structure via PubChem · Public domain (PubChem)
سفارانولین
Sign in to saveCepharanoline is an isolate of Stephania that has antiplasmodial activity with an IC50 of 0.2 μM.
Chemical data
- Formula
- C36H36N2O6
- Molecular weight
- 592.7 g/mol
- IUPAC name
- (14S,27R)-33-methoxy-13,28-dimethyl-2,5,7,20-tetraoxa-13,28-diazaoctacyclo[25.6.2.216,19.13,10.121,25.04,8.031,35.014,39]nonatriaconta-1(33),3(39),4(8),9,16(38),17,19(37),21,23,25(36),31,34-dodecaen-22-ol
- SMILES
- CN1CCC2=CC3=C(C4=C2[C@@H]1CC5=CC=C(C=C5)OC6=C(C=CC(=C6)C[C@@H]7C8=CC(=C(C=C8CCN7C)OC)O4)O)OCO3
- InChIKey
- VQAWRQZAAIQXHM-IZLXSDGUSA-N
- XLogP
- 6.2
- Polar surface area
- 72.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- isoquinoline alkaloid
- Mass
- 592.257337
Show 3 more facts
- chemical formula
- C₃₆H₃₆N₂O₆
- isomeric SMILES
- CN1CCC2=CC3=C(C4=C2[C@@H]1CC5=CC=C(C=C5)OC6=C(C=CC(=C6)C[C@@H]7C8=CC(=C(C=C8CCN7C)OC)O4)O)OCO3
- canonical SMILES
- CN1CCC2=CC3=C(C4=C2C1CC5=CC=C(C=C5)OC6=C(C=CC(=C6)CC7C8=CC(=C(C=C8CCN7C)OC)O4)O)OCO3
Sources (1)
via Wikidata · CC0