CGAS
Sign in to saveAlso known as C6orf150, h-cGAS, Mab-21 domain containing 1, MB21D1, cyclic GMP-AMP synthase, Cyclic GMP-AMP synthase
Cyclic GMP-AMP synthase is a protein that in humans is encoded by the CGAS gene. It's an enzyme, a nucleotidyltransferase, a cyclic GMP-AMP synthase. == References ==
Gene data
CGAS- Name
- cyclic GMP-AMP synthase
- Type
- protein-coding
- Position
- 73,413,515–73,461,726 (−)
- Aliases
- C6orf150, D4, MB21D1, h-cGAS
- Ensembl
- ENSG00000164430
- RefSeq RNA
- NM_001410911.1, NM_138441.3
- RefSeq protein
- NP_001397840.1, NP_612450.2
Enables several functions, including 2',3'-cyclic GMP-AMP synthase activity; chromatin binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including cellular response to exogenous dsRNA; positive regulation of intracellular signal transduction; and regulation of defense response. Located in several cellular components, including cytosol; nucleus; and site of double-strand break. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
cyclic GMP-AMP synthase
- Symbol
- CGAS
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:73,413,515-73,461,726
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 6 more facts
- HomoloGene ID
- 51384
- genomic start
- 74123238
- exact match
- identifiers.org/ncbigene/115004
- genomic end
- 73452297
- cytogenetic location
- 6q13
- Commons category
- Cyclic GMP-AMP Synthase
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- References
- Further reading
- External links
Cyclic GMP-AMP synthase is a protein that in humans is encoded by the CGAS gene. It's an enzyme, a nucleotidyltransferase, a cyclic GMP-AMP synthase. == References ==
== Further reading ==