CHFR

Name

checkpoint with forkhead and ring finger domains

Type

protein-coding

Position

132,822,187–132,956,304 (−)

Aliases

RNF116, RNF196

Ensembl

ENSG00000072609

RefSeq RNA

NM_001161344.1, NM_001161345.1, NM_001161346.2, NM_001161347.1, NM_018223.2

RefSeq protein

NP_001154816.1, NP_001154817.1, NP_001154818.1, NP_001154819.1, NP_060693.2

This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014].

via MyGene.info

Gene · Ensembl

checkpoint with forkhead and ring finger domains

Symbol

CHFR

Biotype

Protein coding

Organism

Homo sapiens

Location

12:132,822,187-132,956,304

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein CHFR PDB 1lgp.png

via Wikidata · CC0